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Longle Ma
Associate
Patents and Innovations
Boston
longle.ma@wsgr.com

D617-598-7889

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Dr. Longle Ma is an associate in the Boston office of Wilson Sonsini Goodrich & Rosati, where his practice focuses on preparation and prosecution of patents in technical areas spanning from chemistry and pharmaceuticals to biotechnology. Longle assists clients in strategical creation and management of patent portfolios and counsels clients on freedom-to-operate and patentability analyses.

Prior to joining the firm, Longle was an associate and a patent agent at a Boston-based law firm where he advised clients of various stages on intellectual property matters in the field of small molecule, nucleic acid, and peptide therapeutics, organic chemistry, specialty materials, and biotechnology. Longle was a postdoctoral fellow at Massachusetts General Hospital/Harvard Medical School working on radiochemistry and development of radiotracers for medical imaging. He received his Ph.D. from Rutgers University where his graduate research was focused on the development of C–H bond functionalization methodology and synthesis of natural products.

Experience

Dr. Longle Ma is an associate in the Boston office of Wilson Sonsini Goodrich & Rosati, where his practice focuses on preparation and prosecution of patents in technical areas spanning from chemistry and pharmaceuticals to biotechnology. Longle assists clients in strategical creation and management of patent portfolios and counsels clients on freedom-to-operate and patentability analyses.

Prior to joining the firm, Longle was an associate and a patent agent at a Boston-based law firm where he advised clients of various stages on intellectual property matters in the field of small molecule, nucleic acid, and peptide therapeutics, organic chemistry, specialty materials, and biotechnology. Longle was a postdoctoral fellow at Massachusetts General Hospital/Harvard Medical School working on radiochemistry and development of radiotracers for medical imaging. He received his Ph.D. from Rutgers University where his graduate research was focused on the development of C–H bond functionalization methodology and synthesis of natural products.

Education
  • J.D., Boston College Law School, 2023

    Cum Laude

  • Ph.D., Organic Chemistry, Rutgers University, 2015
  • B.S., Chemistry, Nankai University, 2010
Admissions
  • State Bar of Massachusetts
  • U.S. Patent and Trademark Office
Credentials
Education
  • J.D., Boston College Law School, 2023

    Cum Laude

  • Ph.D., Organic Chemistry, Rutgers University, 2015
  • B.S., Chemistry, Nankai University, 2010
Admissions
  • State Bar of Massachusetts
  • U.S. Patent and Trademark Office

Select Publications

  • Co-author with A. Paul, H. S. Chandak, and D. Seidel, “Redox-Annulations of Cyclic Amines with ortho-Cyanomethylbenzaldehydes,” 22 Org. Lett. 976-980, 2020
  • Co-author with W. Chen, A. Paul, and D. Seidel, “Direct α-C–H Bond Functionalization of Unprotected Cyclic Amines,” 10 Nat. Chem. 165-169, 2018
  • Co-author with M. S. Placzek, J. M. Hooker, N. Vasdev, and S. Liang, “[11C]Cyanation of Arylboronic Acids in Aqueous Solutions,” 53 Chem. Commun. 6597–6600, 2017
  • Co-author with H. S. Krishnan, N. Vasdev, and S. H. Liang, “18F-Labeling of Sensitive Biomolecules for Positron Emission Tomography,” 23 Chem. Eur. J. 15553–15577, 2017
  • Co-author with A. Paul, M. Brugst, and D. Seidel, “Redox-Neutral Aromatization of Cyclic Amines: Mechanistic Insights and Harnessing of Reactive Intermediates for Amine α- and β-C–H Functionalization,” 22 Chem. Eur. J. 18179–18189, 2016
  • Co-author with W. Chen and D. Seidel, “Redox-Neutral α-Cyanation of Amines,” 134 J. Am. Chem. Soc. 15305–15308, 2012
Insights

Select Publications

  • Co-author with A. Paul, H. S. Chandak, and D. Seidel, “Redox-Annulations of Cyclic Amines with ortho-Cyanomethylbenzaldehydes,” 22 Org. Lett. 976-980, 2020
  • Co-author with W. Chen, A. Paul, and D. Seidel, “Direct α-C–H Bond Functionalization of Unprotected Cyclic Amines,” 10 Nat. Chem. 165-169, 2018
  • Co-author with M. S. Placzek, J. M. Hooker, N. Vasdev, and S. Liang, “[11C]Cyanation of Arylboronic Acids in Aqueous Solutions,” 53 Chem. Commun. 6597–6600, 2017
  • Co-author with H. S. Krishnan, N. Vasdev, and S. H. Liang, “18F-Labeling of Sensitive Biomolecules for Positron Emission Tomography,” 23 Chem. Eur. J. 15553–15577, 2017
  • Co-author with A. Paul, M. Brugst, and D. Seidel, “Redox-Neutral Aromatization of Cyclic Amines: Mechanistic Insights and Harnessing of Reactive Intermediates for Amine α- and β-C–H Functionalization,” 22 Chem. Eur. J. 18179–18189, 2016
  • Co-author with W. Chen and D. Seidel, “Redox-Neutral α-Cyanation of Amines,” 134 J. Am. Chem. Soc. 15305–15308, 2012

Therapeutics and Drug Discovery

  • Small molecule synthesis
  • Small molecules

Chemistry and Material Science

  • Catalysis
  • Chemical synthesis
  • Chemistry
  • Organic chemistry
  • Organometallics
  • Polymorph
  • Process chemistry

Miscellaneous

  • Formulations
Technical Fluency

Therapeutics and Drug Discovery

  • Small molecule synthesis
  • Small molecules

Chemistry and Material Science

  • Catalysis
  • Chemical synthesis
  • Chemistry
  • Organic chemistry
  • Organometallics
  • Polymorph
  • Process chemistry

Miscellaneous

  • Formulations
Focus Areas
  • Biotech
  • Intellectual Property
  • Life Sciences
  • Patents and Innovations
Recent Insights
Client Highlights
Wilson Sonsini Advises General Atlantic on IP Matters Related to Verdiva Bio’s Formation and $410 Million Series A
On January 9, 2025, Verdiva Bio Limited announced its launch as a clinical-stage biopharmaceutical company focused on developing innovative therapies for obesity and other cardiometabolic disorders. Verdiva launched with an oversubscribed Series A financing of $411 million, co-led by General Atlantic and Forbion, with additional participation from RA Capital Management, OrbiMed, Logos Capital, Lilly Asia Ventures, and LYFE Capital (collectively, “the Investor Group”). Wilson Sonsini Goodrich & Rosati advised General Atlantic on IP matters related to Verdiva’s formation and Series A funding round.

Verdiva is advancing a portfolio of next-generation oral and injectable treatments with first-in-class or best-in-class potential. The company is committed to developing next-generation therapies to help people living with obesity, cardiometabolic disorders, and related complications achieve better outcomes via more patient-friendly therapeutic options. Verdiva’s most advanced therapy is VRB-101, an oral GLP-1 peptide in clinical development that has demonstrated best-in-class efficacy potential in a phase 1 study in Australia.
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