Intellectual Property


Dr. Xiaofan (Frank) Yang is a senior associate in the San Diego office of Wilson Sonsini Goodrich & Rosati, where he provides strategic intellectual property counseling to more than 20 growth enterprises in the pharmaceutical, biotechnology, and medical device industries. He works with both venture-backed and public companies. His expertise includes patent strategic counselling and patent prosecution to support life science growth enterprises in all stages of development, from proof of concept to clinical development, to regulatory approval, and to product launch. He also specializes in patent diligence (both buyer and seller side) for venture financings, public offerings, partnering transactions, and mergers and acquisitions. He trains and leads a talented team of patent associates and patent agents that are ready to meet technical and strategic needs of life science companies in patent-related matters.

Prior to joining Wilson Sonsini Goodrich & Rosati, Frank worked as an associate/patent agent for more than five years at an IP boutique firm in Chicago, where he gained wide-ranging and in-depth experience and expertise in patent prosecution and counseling in chemical formulation, medical device, nanotechnology, and green technology. Frank also worked as a medicinal chemist for Solvay Organics GmbH and Bayer Pharmaceuticals for more than four years before he switched to the patent professional career.

  • Otonomy in intellectual property matters leading to its $100 million IPO and follow-up offerings
  • Denali Therapeutics in intellectual property matters related to its $250 million IPO
  • Representation of intellectual property matters leading to other IPOs: MEI Pharma, Crinetics, Harpoon, TCR2, Synthorx, Cirius, Amicus, Alphamab Oncology (HKIPO)
  • Peloton Therapeutics in its $2.2 billion acquisition by Merck
  • United Therapeutics in various large licensing and M&A transactions (Arena Pharmaceuticals, Celularity, MannKind, and Sammumed)
  • Denali Therapeutics in its large licensing/collaboration transactions (Takeda and Sanofi)
  • Paragon Bioteck in intellectual property matters, including unconventional claim strategy leading to the country's first Orange Book patent upheld in PGR challenges (Paragon-Altaire PGR win)
  • Otonomy in PTAB interference proceeding against Auris Medical, including designing of interference strategy leading to Otonomy-Auris interference/appeal win
  • Various ventures in patent due diligence matters from early- to late-series investments
  • More than 15 pharmaceutical and biotech companies in patent due diligence matters from early- to late-series financing
  • J.D., Chicago-Kent College of Law, 2011
  • Ph.D., Organic Chemistry, Tulane University, 2004
  • B.S., Polymer Chemistry, Nanjing University, China, 1997
  • Co-awardee of the 2001 Presidential Green Chemistry Challenge Award (academic) for his work and contributions to the development of environmentally friendly chemical processes
  • Co-author with M. Wang, Y. Zhang, and C.-J. Li, "2,4-Diaryltetrahydropyran Formation by the Prins Cyclization and Its Application towards the Synthesis of Epicalyxin F and Calyxin I," 12 SYNLETT 1912-1916, 2005
  • Co-author with M. Wang and C.-J. Li, "Ruthenium catalyzed tandem olefin-migration/aldol and Mannich-type reactions in ionic liquid," 214 Journal of Molecular Catalysis A: Chemical 147-154, 2004
  • Co-author with M. Wang and C.-J. Li, "Aldol- and Mannich-type reactions via in situ olefin migration in ionic liquid," 5 Organic Letters 657-660, 2003
  • Co-author with M. Wang and C.-J. Li, "Ruthenium-catalyzed tandem olefin migration/aldol and Mannich-type reactions in water and protic solvents," European Journal of Organic Chemistry 998-1003, 2003
  • Co-author with J. T. Mague and C.-J. Li, "Diastereoselective synthesis of polysubstituted tetrahydropyrans and thiacyclohexanes via indium trichloride mediated cyclizations," 66 Journal of Organic Chemistry 739-747, 2001
  • Co-author with C.-J. Li, "Diastereoselective synthesis of multi-substituted thiacyclohexanes via cation-olefine cyclization," 41 Tetrahedron Letters 1321-1325, 2000
  • State Bar of California
  • U.S. Patent and Trademark Office

Contact Information

12235 El Camino Real
San Diego, CA 92130
Phone | 858-350-2339

Email | Frank Yangfyang@wsgr.com

Areas of Expertise

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